Biochemistry: Amino acids and protein structure · Amino Acid Structure and Properties
How amino acids are built, how their side chains and charges behave, and why those properties shape proteins and health.
For learning, not medical advice: for your own health, ask a doctor or another qualified professional.
Try 3 questions
1. What distinguishes one of the 20 standard amino acids from another?
- Its side chain (R group)
- Its carboxyl group
- Its amino group
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Answer: Its side chain (R group)
All share the same backbone: an alpha carbon bearing an amino group, a carboxyl group and a hydrogen; only the side chain differs.
2. Why is every standard amino acid except glycine chiral?
- Its alpha carbon bears four different groups
- Its side chain always contains a ring
- Its amino group is always charged
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Answer: Its alpha carbon bears four different groups
A carbon with four different substituents has non-superimposable mirror images; glycine's side chain is a second hydrogen, so its alpha carbon is not a stereocenter.
3. Which configuration do the amino acids built into human proteins have?
- The D configuration
- An equal mix of L and D
- The L configuration
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Answer: The L configuration
Ribosomes incorporate only L-amino acids; D forms do occur in nature, for example in bacterial cell walls, but not in our ribosome-made proteins.
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