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From Human Physiology: Membrane transport and resting potential · Diffusion and Osmosis

Lung scarring thickens the walls between air and blood. Why does oxygen uptake fall?

  1. Diffusion slows as the distance grows
  2. Oxygen then needs carrier proteins
  3. Thick walls actively pump oxygen out
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Answer: Diffusion slows as the distance grows

By Fick's law, diffusion rate is inversely proportional to membrane thickness, so thicker barriers pass less gas per second.

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